menopausal bleed; muscular weakness; muscle pain; flu like symptoms; cold; headache; tiredness; this is a spontaneous report received from a contactable reporter (consumer or other non hcp) from the regulatory authority. other case identifier: gb-mhra-vac-202202131301491810-mdvsp, gb-mhra-adr 26598398. a 52 year-old female patient received bnt162b2 (comirnaty), administration date 17jan2022 (lot number: 7n3543) as dose number unknown, single for covid-19 immunisation. relevant medical history included: "allergic reaction", start date: may2021 (not ongoing); "rash", start date: may2021 (not ongoing); "i am in my menopause" (unspecified if ongoing), notes: i am in my menopause. last period 8 months ago. there were no concomitant medications. the following information was reported: postmenopausal haemorrhage (medically significant) with onset 12feb2022, outcome "not recovered", described as "menopausal bleed"; muscular weakness (non-serious) with onset 24jan2022, outcome "recovered", described as "muscular weakness"; myalgia (non-serious) with onset 24jan2022, outcome "unknown", described as "muscle pain"; influenza like illness (non-serious) with onset 2022, outcome "recovered", described as "flu like symptoms"; nasopharyngitis (non-serious) with onset 2022, outcome "recovered", described as "cold"; headache (non-serious) with onset 2022, outcome "recovered", described as "headache"; fatigue (non-serious) with onset 2022, outcome "recovered", described as "tiredness". clinical course: no medical history. not taking medicine. patient was in her menopause. last period 8 months ago. date of last menstrual period was 01jul2021. exactly 1 week after the vaccine, patient experienced suddenly muscle weakness and muscle pain, followed by 10 days of flu like symptoms, a cold, headaches tiredness and muscle weakness, then unexpected menstrual bleeding after 8 months of no periods. the medicine was obtained at a "church hall/pharmacy organised." no follow-up attempts are possible. no further information is expected