anaphylactic reaction; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority (ra). the reporter is the patient. other case identifier(s): gb-mhra-vac-202202142206129470-rcso6, gb-mhra-adr 26604621. a 34 year-old female patient (not pregnant) received bnt162b2 (comirnaty), administration date 06aug2021 (lot number: fe3380) as dose number unknown, single for covid-19 immunisation. relevant medical history included: "urticaria chronic" (unknown if ongoing). patient is not currently breastfeeding. patient last menstrual period date was 20jan2022. concomitant medication(s) included: hydroxyzine hydrochloride taken for urticaria, start date: 01apr2010, stop date: 14feb2022. the following information was reported: anaphylactic reaction (medically significant, life threatening) with onset 15aug2021, outcome "recovered" (15aug2021), described as "anaphylactic reaction". the event "anaphylactic reaction" was evaluated at the emergency room visit. patient made it to a&e just in time before she stopped breathing. patient did not think that this reaction occurred as a result of a mistake made in the administration of the vaccine. no follow-up attempts are possible. no further information is expected