itching; primary immunisation: astrazeneca; booster: comirnaty; primary immunisation: astrazeneca; booster: comirnaty; allergic reaction; hives; burning sensation of the skin; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the medicines and healthcare products regulatory agency (uk-mhra). regulatory number: gb-mhra-webcovid-202202231139368450-jknsq (mhra). other case identifier(s): gb-mhra-adr 26639876 (mhra). a 42 year-old male patient received bnt162b2 (comirnaty), administration date 14feb2022 (lot number: fm3092) as dose 3 (booster), single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. vaccination history included: covid-19 vaccine astrazeneca (dose 2), administration date: 21jun2021, for covid-19 immunisation; covid-19 vaccine astrazeneca (dose 1), administration date: 21mar2021, for covid-19 immunisation. the patient had no symptoms associated with covid-19 and was not enrolled in clinical trial. the following information was reported: off label use (medically significant), interchange of vaccine products (medically significant) all with onset 14feb2022, outcome "unknown" and all described as "primary immunisation: astrazeneca; booster: comirnaty"; hypersensitivity (medically significant) with onset feb2022, outcome "not recovered", described as "allergic reaction"; urticaria (medically significant) with onset feb2022, outcome "not recovered", described as "hives"; pruritus (medically significant) with onset 16feb2022, outcome "not recovered", described as "itching"; skin burning sensation (medically significant) with onset feb2022, outcome "unknown", described as "burning sensation of the skin". the events "allergic reaction", "hives", "itching" and "burning sensation of the skin" were evaluated at the physician office visit, doctors appointment was reported. the patient underwent the following laboratory tests and procedures: sars-cov-2 test: no - negative covid-19 test. the patient had not been tested positive for covid-19 since having the vaccine. no follow-up attempts are needed. no further information is expected