skin problems. swelling, redness, pain etc. on legs/very strong painful side effect after pfizer vaccine; skin problems. swelling, redness, pain etc. on legs/legs skin problem; skin problems. swelling, redness, pain etc. on legs; skin problems. swelling, redness,; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the regulatory authority. the reporter is the patient. regulatory number: ie-ra-2022-092099 (ra). other case identifier(s): ie-ra-hmarr-2022012911343 (ra). a 73 year-old female patient received bnt162b2 (comirnaty), administration date 20apr2021 (lot number: fh8469) at the age of 73 years as dose 1, single for covid-19 immunisation. relevant medical history included: "heart attack/embolic heart attack" (unspecified if ongoing); "ischemic stroke" (unspecified if ongoing), notes: 2 ischemic strokes; "hypertension" (unspecified if ongoing); "atrial fibrillation" (unspecified if ongoing). there were no concomitant medications. the following information was reported: pain in extremity (medically significant) with onset 20apr2021, outcome "not recovered", described as "skin problems. swelling, redness, pain etc. on legs/very strong painful side effect after pfizer vaccine"; skin disorder (medically significant) with onset 20apr2021, outcome "not recovered", described as "skin problems. swelling, redness, pain etc. on legs/legs skin problem"; skin swelling (medically significant) with onset 20apr2021, outcome "not recovered", described as "skin problems. swelling, redness, pain etc. on legs"; erythema (medically significant) with onset 20apr2021, outcome "not recovered", described as "skin problems. swelling, redness,". therapeutic measures were taken as a result of pain in extremity, skin disorder, skin swelling, erythema and included "antibiotics 3 courses, tablets and cream...antibiotics treatment does not work" (as reported). reporter commented: "i have very strong painful side effect after pfizer vaccine, legs skin problem, swelling, redness, etc. start after first jab, after second got worse after booster is absolutely bad. is treatment to help or no? i had 3 courses treatment with antibiotics tablets and cream but did not help." no follow-up attempts are possible. no further information is expected. sender's comments: linked report(s) : ie-pfizer inc-202200300543 same patient, vaccine and different dose number and event