otosclerosis; almost total loss of left ear hearing; increased tinnitus; off label use; interchange of vaccine products; this is a spontaneous report received from a contactable reporter(s) (consumer or other non hcp) from the medicines agency () -web. regulatory number: it-minisal02-844655 (minisal02). a 59 year-old male patient received bnt162b2 (comirnaty), intramuscular, administered in arm right, administration date 09feb2022 (batch/lot number: unknown) as dose 2 (pfizer initial), single for covid-19 immunisation. the patient's relevant medical history and concomitant medications were not reported. vaccination history included: moderna (dose 1), for covid-19 immunisation. the following information was reported: hypoacusis (disability) with onset 11feb2022, outcome "not recovered", described as "almost total loss of left ear hearing"; tinnitus (disability) with onset 11feb2022, outcome "not recovered", described as "increased tinnitus"; otosclerosis (non-serious) with onset 11feb2022 22:15, outcome "unknown", described as "otosclerosis"; off label use (non-serious) with onset 09feb2022, outcome "unknown", described as "off label use"; interchange of vaccine products (non-serious) with onset 09feb2022, outcome "unknown", described as "interchange of vaccine products". reporter comment: vaccination with moderna as the first dose. - no flu vaccination was carried out - concomitant conditions: bilateral otosclerosis with tinnitus - reaction time: 22:15 - posted by vigicovid19-tab. no follow-up attempts are possible; information about lot/batch number cannot be obtained. no further information is expected.; reporter's comments: vaccination with moderna as the first dose. - no flu vaccination was carried out - concomitant conditions: bilateral otosclerosis with tinnitus - reaction time: 22:15 - posted by vigicovid19-tab